Exterminator in its current state has no practical use in a raid whatsoever, as most NPCs have a minimum of strong difficoulty. However, if you add an instakill for strong / elite npc-s as well with a lower health requirement (Strong: 20% Elite: 13% or something) it might actually be viable. Or if you change it entirely, Annihilate enables the next Vicious Throw to be used on any health %
Rapid Rupture seems okay as it is, adapting the rotation to refresh it 1 GCD earlier shouldn't be a problem as long as it doesn't interfere with higher priority abilities.
Vicious Saber seems a little less useful to me, as it is - in essence - shortening the DoT uptime on the boss. The way it works now is you apply each stack with a weapon hit, so you can space them out a little, squeezing a little more damage out, so it's on the target for not 6 but a minimum of 10,5 seconds - which is potentially more damage than having it go out all at once. For burst, this is clearly better, but overall it will do less damage. Instead, it could be changed to this: Hitting an enemy with 3 Deadly Saber stacks on it, while you have stacks left refreshes the DoT duration on the target. This would bring Anni to be a very strong DoT spec, it'd be up to the player to achieve enough uptime and space out DoT applications so that they can keep it on the target. Adapting playstyles is the main reason for Tactical Items in the first place, isn't it?