Those guys are either male or female personalities, so they would be able to fit in with the female and male threads already established.
They have been programmed to have either a male orientated view programmed into them or a female one, I think Scorpio for this one (although I'm not familiar with IA companions).
Qyzen is quite obviously a male.
SCORPIO is the only non-biological female companion, and some people do go in for dat voice. Every possibly-ambiguous companion (Blizz, Broonmark, Qyzen, etc.) in the game is explicitly stated in the Codex to be male.