It happens about every 45 mins to an hour. My mouse will not work with my interface. I can select NPC's and other players... use hot keys... do anything I want until I have to right click add invite or select a flight path, choose a reward option, etc. IT IS ABSOLUTELY F***ING ANNOYING and makes me want to through the damn game away.

To fix the problem I have to ctrl+alt+delete and end task to kill the game and then log back in. you know how DAMN annoying that is.