Acendancy:
when you pass the mine layer for the first time, there are to fighter flying away on the right. one flies off completly to the right the other one makes a turn back towards the centre and than back at you. that is the 4th heavy. Clouds:
unload your missiles on the first 3 cruiser that fly at you for their turrets, engines and shield generators, ignore the second pair of fighter there
use your protons for the first 3 capital shield generators and the bridge and fire at capital turrets on the first drive by of the big one
use your EMP Burst when you are on top of the 2 cruiser after the first run on the capital shield generators, this leaves you plenty of time for fighter shooting at the same time.
don't hesitate shooting missiles at fighters (having 150 helps!) Mulgor:
unload on lower shield generator on the first drive by, if it's not enough to take it out than, do not shoot it again on the second drive but focus on the upper one as this one stays shootable longer on the second run. finish both of with your EMP burst.
managing the last one is almost harder as you only get 1 attempt at both.