I don't bind anything with a long cooldown. My Naga has 8 buttons programmed for combat abilities/macros and the rest are for things like select closest target, target of target, pass the Huttball. The 1 and 2 keys bound to buttons on my Nostromo.
I could probably revamp my UI, but this works for my "get out of the way, we're trying to score in Huttball" playstyle.
Also empty spaces notwithstanding, I was trying out glass cannon earlier spec that evening.