There is an easy easy way.
Enter area Kill first group re-route first one exit instance reset instance enter instance kill first group re-route 1-3 and die. You kill the first group because solo you can re-route the next two without killing anything before you die.
To do the above you need to "finish" this instance last. I collect all missions. Enter area and kill to this one. Start it and leave. Kill to Hypermatter Directive
Note, all items in this can be gotten without tripping anything. If you have 4 people you can all go to separate box and not trip for faster completing. For two you stand on a box and won't get detected. For two you run in and out fast. One can just be gotten.
Exit, finish area one, EoT, than complete the run and die. Pop right back to base to complete.